Phenylalanine

Phenylalanine

SCHEMBL304849

CC(C)C[C@H](N)C(=O)O.CSCC[C@H](NC=O)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.50
FNTA P49354 7/20 0.47
FNTB P49356 7/20 0.47
PGGT1B P53609 5/20 0.47
ALPI P09923 1/20 0.47
PKM P14618 1/20 0.47
PTGS1 P23219 1/20 0.47
XIAP P98170 1/20 0.47
SLC7A5 Q01650 1/20 0.47
KMT2A Q03164 1/20 0.46
FPR1 P21462 1/20 0.45
FPR2 P25090 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL7222094 1.00 LTA4H (0.50) LTA4HFNTAFNTBPGGT1BALPI
Dl-Phenylalanine SCHEMBL21722624 0.90 FPR1 (0.55) LTA4HFNTAFNTBPGGT1BFPR1
Phenylalanine SCHEMBL3455844 0.90 FPR1 (0.55) LTA4HFNTAFNTBPGGT1BFPR1
SCHEMBL856024 0.89 FNTA (0.54) LTA4HFNTAFNTBPGGT1BFPR1
SCHEMBL18106731 0.89 FNTA (0.54) LTA4HFNTAFNTBPGGT1BFPR1
Leucine SCHEMBL1393748 0.88 SLC7A5 (0.50) FNTAFNTBPGGT1BSLC7A5FPR1
Phenylalanine SCHEMBL907512 0.85 SLC7A5 (0.58) LTA4HFNTAFNTBPGGT1BALPI
D-Phenylalanine SCHEMBL6450960 0.85 SLC7A5 (0.58) LTA4HFNTAFNTBPGGT1BALPI
Phenylalanine SCHEMBL7263675 0.83 FPR1 (0.51) FNTAFNTBPGGT1BFPR1FPR2
SCHEMBL61200 0.82 ANPEP (0.43) LTA4HFNTAFNTBPGGT1BFPR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2573569-A1 Antibodies, compositions, and assays for detection of cardiac disease Nour Heart, Inc. (US) 2013-03-27 EP claimed
US-8377685-B2 Microfluidic device having stable static gradient for analyzing chemotaxis BELLBROOK LABS, LLC (US) 2013-02-19 US claimed
US-20120216303-A1 NOVEL THERAPEUTIC USES OF HUMAN FORMYL PEPTIDE RECEPTOR ANTAGONISTS NIKAN PHARMACEUTICALS, LLC (US) 2012-08-23 US claimed
EP-2214828-A1 MICROFLUIDIC DEVICE HAVING STABLE STATIC GRADIENT FOR ANALYZING CHEMOTAXIS Bellbrook Labs, Llc (US) 2010-08-11 EP claimed
US-20090123961-A1 MICROFLUIDIC DEVICE HAVING STABLE STATIC GRADIENT FOR ANALYZING CHEMOTAXIS BELLBROOK LABS, LLC 2009-05-14 US claimed
WO-2009062095-A1 MICROFLUIDIC DEVICE HAVING STABLE STATIC GRADIENT FOR ANALYZING CHEMOTAXIS BELLBROOK LABS, LLC (US) 2009-05-14 WO claimed
US-20080260650-A1 Methods of Detection and Therapy of Inflamed Tissues Using Immune Modulation THE GENERAL HOSPITAL CORPORATION (US) 2008-10-23 US claimed
US-20080193376-A1 Methods of Enhanced Detection and Therapy of Inflamed Tissues Using Immune Modulation THE GENERAL HOSPITAL CORPORATION (US) 2008-08-14 US claimed
WO-2006049599-A1 METHODS OF DETECTION AND THERAPY FOR ATHEROMATOUS PLAQUES USING IMMUNE MODULATION THE GENERAL HOSPITAL CORPORATION (US) 2006-05-11 WO claimed
WO-2006050058-A2 METHODS OF DETECTION AND THERAPY OF INFLAMED TISSUES USING IMMUNE MODULATION THE GENERAL HOSPITAL CORPORATION (US) 2006-05-11 WO claimed
US-20040261140-A1 Transgenic mice expressing human formyl peptide receptor NIKAN PHARMACEUTICALS, LLC 2004-12-23 US claimed
US-6699905-B2 COMPRISING ADMINISTERING TO THE SUBJECT AN EFFECTIVE ANTI-INFLAMMATORY AMOUNT OF A PHARMACEUTICAL COMPOSITION COMPRISING A LIPOXIN A4 COMPOUND AND A PHARMACEUTICALLY ACCEPTABLE CARRIER BRIGHAM AND WOMEN'S HOSPITAL 2004-03-02 US claimed
US-20030060512-A1 Modulation of inflammation related to columnar epithelia MADARA JAMES L (US) 2003-03-27 US claimed
US-20020045579-A1 Modulation of inflammation related to columnar epithelia MADARA JAMES L (US) 2002-04-18 US claimed
US-4970162-A Human-mouse hybrid cell line expressing monocyte-macrophage properties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1990-11-13 US claimed
EP-4710935-A2 NOVEL IMMUNOTHERAPEUTIC COMPOSITION AND USES THEREOF Aravax Pty Ltd (AU) 2026-03-18 EP disclosed
WO-2024128630-A1 BLOOD PERFUSION DEVICE FOR REDUCING SECONDARY NOSOCOMIAL INFECTIONS IN HOSPITAL 서울대학교산학협력단 2024-06-20 WO disclosed
US-4986979-A Imaging tissue sites of inflammation NEORX CORPORATION 1991-01-22 US disclosed
US-4970162-A Human-mouse hybrid cell line expressing monocyte-macrophage properties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1990-11-13 US disclosed
US-4970162-A Human-mouse hybrid cell line expressing monocyte-macrophage properties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1990-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030060512-A1 Modulation of inflammation related to columnar epithelia LTB4R2, ALOX15B, LTB4R LTA4H 10/4885FNTA 1165/4885FNTB 1729/4885
US-20020045579-A1 Modulation of inflammation related to columnar epithelia LTB4R2, ALOX15B, LTB4R LTA4H 10/4885FNTA 1165/4885FNTB 1729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.