SCHEMBL7711735

SCHEMBL7711735

O=C1C2=C(CCCC2)C(=O)N1c1ccc(Cl)c(O)c1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.47
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
BCL2A1 Q16548 1/20 0.38
PIM3 Q86V86 1/20 0.38
HIPK4 Q8NE63 1/20 0.38
SCN2A Q99250 1/20 0.38
NR1H3 Q13133 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7163791 0.81 PPOX (0.69) PPOXMAPTKMT2ABCL2A1
SCHEMBL9807518 0.81 PPOX (0.47) PPOXMAPTKMT2ABCL2A1
SCHEMBL11013114 0.81 PPOX (0.40) PPOXKMT2APIM3HIPK4SCN2A
SCHEMBL8560334 0.80 TDP1 (0.50) PPOXMAPTPIM3HIPK4SCN2A
SCHEMBL9737192 0.80 PPOX (0.44) PPOXBCL2A1
SCHEMBL10598966 0.80 PPOX (0.44) PPOXMAPTKMT2ABCL2A1
SCHEMBL12362765 0.80 KMT2A (0.47) MAPTKMT2A
SCHEMBL9765179 0.79 PPOX (0.43) PPOXMAPT
SCHEMBL9737247 0.79 ALDH1A1 (0.62) PPOXMAPTKMT2A
SCHEMBL9549608 0.79 MMP2 (0.46) PPOXMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE37664-E1 Use of derivatives of N-phenl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs BASF AKTIENGESSELLSCHAFT (DE) 2002-04-16 US disclosed
EP-0385231-B1 Use of derivatives of N-phenyl-3,4,5,6-tetrahydrophthalimide in the desiccation and abscission of plant organs BASF AG (DE) 1996-09-18 EP disclosed
EP-0313963-B1 N-PHENYLTETRAHYDROPHTHALIMIDE DERIVATIVES BASF Aktiengesellschaft (DE) 1992-12-23 EP disclosed
US-5169428-A Tetrahydrophthalimide derivative and herbicide composition containing same TOSOH CORPORATION (JP) 1992-12-08 US disclosed
US-5045105-A Use of derivatives of n-phenyl-3,4,5,6-tetrahydrophthalimide for the desiccation and abscission of plant organs BASF AKTIENGESELLSCHAFT (DE) 1991-09-03 US disclosed
EP-0385231-A1 Use of derivatives of N-phenyl-3,4,5,6-tetrahydrophthalimide in the desiccation and abscission of plant organs BASF Aktiengesellschaft (DE) 1990-09-05 EP disclosed
US-4888046-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1989-12-19 US disclosed
EP-0323271-A1 Tetrahydrophthalimide derivative and herbicide composition containing the same Tosoh Corporation (JP) 1989-07-05 EP disclosed
EP-0313963-A1 N-phenyltetrahydrophthalimide derivatives BASF Aktiengesellschaft (DE) 1989-05-03 EP disclosed
US-4536209-A N-(3-substituted oxyphenyl)tetrahydrophthalimides and herbicidal composition MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) 1985-08-20 US disclosed
US-4439229-A Substituted phthalimides herbicides ROHM AND HAAS COMPANY (US) 1984-03-27 US disclosed
EP-0068822-A2 Novel heterocyclic substituted benzenes, herbicidal compositions containing them and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1983-01-05 EP disclosed
EP-0049508-A1 N-(3-Substituted oxyphenyl) tetrahydrophthalimides and herbicidal composition MITSUBISHI KASEI CORPORATION (JP) 1982-04-14 EP disclosed
US-4292070-A N-Substituted tetrahydrophthalimide and herbicidal composition MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1981-09-29 US disclosed