Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 3/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650565 | 0.74 | CCKBR (0.54) | CCKBR | |
| SCHEMBL8563276 | 0.71 | CCKBR (0.50) | CCKBR | |
| SCHEMBL8865968 | 0.65 | CCKBR (0.57) | CCKBR | |
| SCHEMBL21172170 | 0.60 | HTT (0.63) | GAASMN1; SMN2SIRT2LMNA | |
| SCHEMBL8556701 | 0.59 | CCKBR (0.46) | CCKBR | |
| SCHEMBL12132431 | 0.59 | CTSB (0.46) | RAB9ANPC1SMN1; SMN2CTSLCTSB | |
| SCHEMBL13876812 | 0.59 | SMN1; SMN2 (0.56) | RAB9ANPC1MAPK1SMN1; SMN2CTSL | |
| SCHEMBL7378562 | 0.59 | LMNA (0.65) | SMN1; SMN2KCNA5LMNA | |
| SCHEMBL12354336 | 0.58 | FOLH1 (0.48) | GAASMN1; SMN2LMNA | |
| SCHEMBL24447454 | 0.58 | CTSK (0.62) | CTSLCTSBCTSSCTSKSIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |