Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560582 | 1.00 | FADS1 (0.45) | FADS1FAAHMGLLPOLBDRD2 | |
| SCHEMBL14275600 | 0.81 | HTR2C (0.45) | FADS1FAAHMGLLPOLBDRD2 | |
| SCHEMBL965009 | 0.81 | CA12 (0.54) | POLBDRD2DRD3HTR2CALOX5 | |
| SCHEMBL8563716 | 0.81 | CA12 (0.54) | POLBDRD2DRD3HTR2CALOX5 | |
| SCHEMBL1514921 | 0.80 | MEN1 (0.50) | MGLLPOLBROCK2ALDH1A1MEN1 | |
| SCHEMBL8568619 | 0.79 | ROCK2 (0.56) | FADS1MGLLDRD2DRD3ALOX5 | |
| SCHEMBL8568624 | 0.79 | ROCK2 (0.56) | FADS1MGLLDRD2DRD3ALOX5 | |
| SCHEMBL8788607 | 0.79 | DRD2 (0.50) | DRD2DRD3ROCK2 | |
| SCHEMBL892919 | 0.78 | POLB (0.46) | FADS1FAAHMGLLPOLBDRD2 | |
| SCHEMBL29086020 | 0.78 | FADS1 (0.42) | FADS1FAAHMGLLPOLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060778-C | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-17 | — | — | CN | disclosed |
| US-5804577-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1998-09-08 | — | — | US | disclosed |
| CN-1150950-A | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1997-06-04 | — | — | CN | disclosed |
| EP-0761673-A1 | Cephalosporin derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-12 | — | — | EP | disclosed |