Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | USP19 | O94966 | 1/20 | 0.35 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | FABP1 | P07148 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560970 | 0.87 | PTGS1 (0.43) | GRM5PTGS1PTGS2ALOX5TRPV1 | |
| SCHEMBL7502838 | 0.86 | PTGS2 (0.55) | GRM5PTGS1PTGS2ALOX5 | |
| SCHEMBL8558002 | 0.85 | CA12 (0.43) | PTGS1PTGS2ALOX5RXRA | |
| SCHEMBL8559954 | 0.82 | PTGS2 (0.41) | PTGS1PTGS2ALOX5TRPV1USP1 | |
| SCHEMBL8558777 | 0.81 | TDP1 (0.43) | PTGS1PTGS2ALOX5TRPV1RXRA | |
| SCHEMBL8556142 | 0.81 | PTGS2 (0.46) | PTGS1PTGS2TRPV1USP1USP19 | |
| SCHEMBL8555996 | 0.81 | RXRA (0.43) | PTGS1PTGS2ALOX5APFEN1RXRA | |
| SCHEMBL7500629 | 0.80 | PTGS2 (0.56) | GRM5PTGS1PTGS2 | |
| SCHEMBL8558402 | 0.79 | PTGS2 (0.44) | PTGS1PTGS2TRPV1USP1USP19 | |
| SCHEMBL8561129 | 0.79 | PTGS2 (0.44) | PTGS1PTGS2TRPV1USP1USP19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |