Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563739 | 0.83 | KMT2A (0.36) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL8568519 | 0.81 | LMNA (0.36) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL8562399 | 0.75 | POLB (0.43) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL8567950 | 0.74 | CYP3A4 (0.47) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8567837 | 0.73 | KMT2A (0.40) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL8564976 | 0.72 | SMN1; SMN2 (0.39) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL3953291 | 0.72 | KDM4E (0.52) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL12518927 | 0.70 | MAOA (0.48) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL8562456 | 0.70 | CYP3A4 (0.43) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL8567514 | 0.70 | S100A4 (0.54) | ALDH1A1MAPTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |