Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.37 |
| ▸ | MEN1 | O00255 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567837 | 0.78 | KMT2A (0.40) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL3298254 | 0.73 | KMT2A (0.54) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8563739 | 0.72 | KMT2A (0.36) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8568519 | 0.72 | LMNA (0.36) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8560848 | 0.72 | ALDH1A1 (0.38) | KMT2AMEN1MAPTL3MBTL1F2 | |
| SCHEMBL4543383 | 0.72 | ALDH1A1 (0.47) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL8855966 | 0.70 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL8562399 | 0.69 | POLB (0.43) | SMN1; SMN2KMT2AMEN1MAPTF2 | |
| SCHEMBL8569955 | 0.68 | KMT2A (0.42) | SMN1; SMN2KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL3956436 | 0.68 | NCF1 (0.51) | SMN1; SMN2KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |