Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.55 |
| ▸ | HRH1 | P35367 | 5/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | GHSR | Q92847 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | DRD1 | P21728 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556582 | 0.80 | KDM4E (0.61) | KCNH2HRH1OPRK1LMNADRD3 | |
| SCHEMBL588111 | 0.79 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL588110 | 0.79 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL3611802 | 0.79 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL12464946 | 0.79 | KCNH2 (0.80) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588103 | 0.78 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588128 | 0.78 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL587709 | 0.78 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL8556503 | 0.78 | SIGMAR1 (0.58) | KCNH2LMNADRD3DRD2CYP3A4 | |
| SCHEMBL7668121 | 0.76 | CHRM2 (0.83) | KCNH2HRH1OPRK1ADORA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |