Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555562 | 0.84 | DRD4 (0.54) | SIGMAR1ALDH1A1DRD4LMNADRD2 | |
| SCHEMBL8555816 | 0.83 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1DRD4KMT2A | |
| SCHEMBL8558370 | 0.79 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1LMNADRD2DRD3 | |
| SCHEMBL7481150 | 0.78 | ALDH1A1 (0.41) | ALDH1A1POLBKMT2A | |
| SCHEMBL8558421 | 0.78 | ALDH1A1 (0.55) | SIGMAR1ALDH1A1DRD4POLBLMNA | |
| SCHEMBL8560914 | 0.78 | KCNH2 (0.55) | ALDH1A1DRD4LMNADRD2DRD3 | |
| SCHEMBL2489199 | 0.76 | SIGMAR1 (1.00) | SIGMAR1MC4RDRD4POLBLMNA | |
| SCHEMBL576868 | 0.76 | SIGMAR1 (1.00) | SIGMAR1MC4RDRD4POLBLMNA | |
| SCHEMBL8188324 | 0.76 | SIGMAR1 (1.00) | SIGMAR1MC4RDRD4POLBLMNA | |
| SCHEMBL1415730 | 0.76 | SIGMAR1 (1.00) | SIGMAR1MC4RDRD4POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |