Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.43 |
| ▸ | CDK9 | P50750 | 4/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555068 | 0.93 | ALDH1A1 (0.50) | ALDH1A1MAPTSCN9ASLC40A1LMNA | |
| SCHEMBL8559666 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MAPTSLC40A1LMNAHTR6 | |
| SCHEMBL8557580 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MAPTCCNT1CDK9SLC40A1 | |
| SCHEMBL8558287 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTSLC40A1LMNATSHR | |
| SCHEMBL8557951 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTCCNT1CDK9SCN9A | |
| SCHEMBL8557783 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTSCN9ASLC40A1LMNA | |
| SCHEMBL8559996 | 0.85 | CCNT1 (0.41) | ALDH1A1MAPTCCNT1CDK9PLK1 | |
| SCHEMBL8561410 | 0.84 | PTGS2 (0.47) | ALDH1A1MAPTSLC40A1LMNASMN1; SMN2 | |
| SCHEMBL8560974 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTCCNT1CDK9SCN9A | |
| SCHEMBL8560513 | 0.82 | MAPT (0.49) | ALDH1A1MAPTSLC40A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |