Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556679 | 0.93 | ALDH1A1 (0.46) | ALDH1A1MAPTSLC40A1LMNAMCOLN2 | |
| SCHEMBL8557580 | 0.93 | ALDH1A1 (0.46) | ALDH1A1MAPTSLC40A1LMNAMCOLN2 | |
| SCHEMBL8557951 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPTSLC40A1LMNAMCOLN2 | |
| SCHEMBL8559957 | 0.85 | MAPT (0.47) | ALDH1A1MAPTSLC40A1LMNATSHR | |
| SCHEMBL8560355 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTSLC40A1LMNATSHR | |
| SCHEMBL8560974 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTSLC40A1SMN1; SMN2NR3C1 | |
| SCHEMBL8556335 | 0.83 | MAPT (0.44) | ALDH1A1MAPTSLC40A1LMNAMCOLN2 | |
| SCHEMBL8553397 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTSLC40A1LMNAGGT1 | |
| SCHEMBL8560689 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTSLC40A1LMNATSHR | |
| SCHEMBL8557661 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTSLC40A1LMNAGGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |