Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561648 | 0.92 | PIK3CD (0.46) | MAPTTP53PTPN2PTPN1PTPN5 | |
| SCHEMBL8556972 | 0.89 | ALDH1A1 (0.49) | MAPTTP53PTPN2PTPN1PTPN5 | |
| SCHEMBL8560132 | 0.86 | MEN1 (0.47) | MAPTPTPN2PTPN1PTPN5ALDH1A1 | |
| SCHEMBL8557471 | 0.86 | MAPT (0.48) | MAPTPTPN2PTPN1PTPN5ALDH1A1 | |
| SCHEMBL8559429 | 0.86 | AAK1 (0.45) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL8553427 | 0.85 | PIK3CD (0.48) | MAPTTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL8556146 | 0.84 | PGR (0.50) | MAPTTP53PTPN2PTPN1ALDH1A1 | |
| SCHEMBL8556998 | 0.84 | PTPN1 (0.44) | MAPTPTPN2PTPN1PTPN5ALDH1A1 | |
| SCHEMBL8559037 | 0.84 | MAPT (0.46) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8556290 | 0.84 | MAPT (0.51) | MAPTTP53PTPN2PTPN1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |