Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.41 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561015 | 0.92 | MAPT (0.48) | PIK3CGALDH1A1GGT1MAPTTP53 | |
| SCHEMBL8556972 | 0.90 | ALDH1A1 (0.49) | PIK3CGALDH1A1GGT1MAPTTP53 | |
| SCHEMBL8555914 | 0.87 | MAPT (0.43) | SLC40A1ALDH1A1GGT1MAPTTP53 | |
| SCHEMBL8557996 | 0.86 | MAPT (0.46) | SLC40A1ALDH1A1MAPTLMNATSHR | |
| SCHEMBL8559429 | 0.85 | AAK1 (0.45) | SLC40A1ALDH1A1MAPTTP53LMNA | |
| SCHEMBL8557471 | 0.85 | MAPT (0.48) | ALDH1A1MAPTLMNATSHRKMT2A | |
| SCHEMBL8553427 | 0.85 | PIK3CD (0.48) | PIK3CDPIK3CGSLC40A1ALDH1A1GGT1 | |
| SCHEMBL8559037 | 0.84 | MAPT (0.46) | PIK3CDPIK3CGSLC40A1ALDH1A1GGT1 | |
| SCHEMBL8556039 | 0.84 | MAPT (0.44) | SLC40A1ALDH1A1MAPTTP53LMNA | |
| SCHEMBL8555551 | 0.84 | MAPT (0.43) | SLC40A1ALDH1A1MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |