Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KAT7 | O95251 | 1/20 | 0.41 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560735 | 0.91 | PTGS2 (0.43) | TSHRMAPTTP53SLC40A1ALDH1A1 | |
| SCHEMBL8560184 | 0.91 | MAPT (0.46) | TSHRMAPTTP53SLC40A1ALDH1A1 | |
| SCHEMBL8555756 | 0.91 | MAPT (0.46) | MAPK1TSHRMAPTTP53SLC40A1 | |
| SCHEMBL8556972 | 0.86 | ALDH1A1 (0.49) | HTTMAPTTP53ALDH1A1LMNA | |
| SCHEMBL9026371 | 0.86 | KMT2A (0.41) | TSHRMAPTTP53SLC40A1PI4KB | |
| SCHEMBL9026127 | 0.86 | MAPT (0.42) | MAPK1MAPTTP53SLC40A1ALDH1A1 | |
| SCHEMBL8561015 | 0.86 | MAPT (0.48) | HTTMAPTTP53ALDH1A1LMNA | |
| SCHEMBL8561648 | 0.85 | PIK3CD (0.46) | TSHRHTTMAPTTP53SLC40A1 | |
| SCHEMBL8553427 | 0.85 | PIK3CD (0.48) | MAPK1MAPTTP53SLC40A1ALDH1A1 | |
| SCHEMBL8558253 | 0.84 | ALDH1A1 (0.44) | MAPK1TSHRHTTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |