Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SDHB | P21912 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18689703 | 0.81 | PDE2A (0.51) | LMNASMN1; SMN2MAOBPDE2AALDH1A1 | |
| SCHEMBL8167810 | 0.78 | PDE2A (0.48) | LMNASMN1; SMN2MAOBPDE2AALDH1A1 | |
| SCHEMBL1067726 | 0.78 | SMN1; SMN2 (1.00) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL8558105 | 0.76 | ALDH1A1 (0.48) | LMNASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL9899908 | 0.76 | PDE2A (0.45) | LMNASMN1; SMN2MAOBPDE2AALDH1A1 | |
| SCHEMBL8562901 | 0.75 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2MAOBALDH1A1HPGD | |
| SCHEMBL8558749 | 0.73 | NUDT1 (0.44) | LMNASMN1; SMN2HPGDCYP19A1NPC1 | |
| SCHEMBL8559618 | 0.73 | NUDT1 (0.44) | LMNASMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL6561352 | 0.72 | SMN1; SMN2 (0.78) | LMNASMN1; SMN2ALDH1A1HPGDMCOLN3 | |
| SCHEMBL6638773 | 0.71 | SMN1; SMN2 (0.65) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726128-A | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0707001-A1 | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-17 | — | — | EP | disclosed |