Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558105 | 0.86 | ALDH1A1 (0.48) | NUDT1SMN1; SMN2LMNAGRM5NPC1 | |
| SCHEMBL8559618 | 0.86 | NUDT1 (0.44) | NUDT1SMN1; SMN2LMNATLR7NPC1 | |
| SCHEMBL8167810 | 0.85 | PDE2A (0.48) | SMN1; SMN2LMNANPC1HPGDRAB9A | |
| SCHEMBL8562901 | 0.84 | SMN1; SMN2 (0.45) | NUDT1SMN1; SMN2LMNATLR7NPC1 | |
| SCHEMBL8560362 | 0.81 | SDHB (0.56) | SMN1; SMN2LMNANPC1HPGDRAB9A | |
| SCHEMBL3543675 | 0.79 | ALKBH1 (0.44) | NUDT1SMN1; SMN2GRM5NPC1AR | |
| SCHEMBL603696 | 0.79 | NUDT1 (0.48) | NUDT1SMN1; SMN2GRM5PKMPTGES | |
| SCHEMBL9432390 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNANPC1RAB9APTGS2 | |
| SCHEMBL8384805 | 0.77 | PIN1 (0.47) | NUDT1GRM5NPC1PKMPTGES | |
| SCHEMBL3930094 | 0.76 | NUDT1 (0.62) | NUDT1SMN1; SMN2LMNAGRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726128-A | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0707001-A1 | Benzyloxypyrimidine derivative, processes for producing the same and herbicidal composition | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-04-17 | — | — | EP | disclosed |