Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL857343 | 0.99 | PTGDR2 (0.41) | PTGDR2ACHESIGMAR1CCR5HTR2A | |
| SCHEMBL856161 | 0.85 | ACHE (0.38) | PTGDR2ACHERORC | |
| SCHEMBL856425 | 0.84 | ACHE (0.36) | ACHESIGMAR1RORC | |
| SCHEMBL3723441 | 0.83 | ACHE (0.35) | ACHEAGER | |
| SCHEMBL857298 | 0.83 | ACHE (0.35) | PTGDR2ACHERORC | |
| SCHEMBL3717335 | 0.82 | AGER (0.34) | ACHEAGER | |
| SCHEMBL856242 | 0.82 | ACHE (0.35) | ACHERORC | |
| SCHEMBL858893 | 0.76 | TP53 (0.35) | ACHE | |
| SCHEMBL856154 | 0.74 | AADAT (0.43) | SIGMAR1 | |
| SCHEMBL856612 | 0.74 | AADAT (0.43) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432779-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | Exelixis, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |