Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KAT7 | O95251 | 1/20 | 0.37 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026127 | 0.93 | MAPT (0.42) | MAPTPOLBALDH1A1LMNAKDM4E | |
| SCHEMBL8560184 | 0.88 | MAPT (0.46) | MAPTPOLBALDH1A1LMNATSHR | |
| SCHEMBL8561648 | 0.87 | PIK3CD (0.46) | MAPTALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL8555756 | 0.86 | MAPT (0.46) | MAPTPOLBALDH1A1LMNATSHR | |
| SCHEMBL8560000 | 0.85 | KMO (0.47) | MAPTALDH1A1LMNATSHRKDM4E | |
| SCHEMBL8556039 | 0.85 | MAPT (0.44) | MAPTALDH1A1LMNATSHRKDM4E | |
| SCHEMBL8553792 | 0.85 | MAPT (0.40) | MAPTPOLBALDH1A1LMNATSHR | |
| SCHEMBL8559699 | 0.85 | MAPT (0.43) | MAPTPOLBALDH1A1LMNATSHR | |
| SCHEMBL8558989 | 0.84 | ALDH1A1 (0.46) | MAPTPOLBALDH1A1LMNATSHR | |
| SCHEMBL8556972 | 0.83 | ALDH1A1 (0.49) | MAPTPOLBALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |