Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | APAF1 | O14727 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CASP1 | P29466 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15474335 | 0.94 | MEN1 (0.66) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8060137 | 0.91 | MEN1 (0.80) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1924100 | 0.87 | HTT (0.78) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL27486404 | 0.84 | HTT (0.63) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4592466 | 0.83 | MAPT (0.69) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9320377 | 0.83 | HTT (0.67) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL2065031 | 0.82 | CYP1A2 (0.69) | MEN1KMT2AALDH1A1HTTCA1 | |
| SCHEMBL22628164 | 0.82 | HTT (0.71) | MEN1KMT2AALDH1A1L3MBTL1HTT | |
| N-Benzylaniline SCHEMBL7840 | 0.82 | HTT (0.71) | MEN1KMT2AALDH1A1L3MBTL1HTT | |
| SCHEMBL11935856 | 0.82 | GAA (0.67) | POLBMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | claimed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | claimed |
| EP-0064199-B1 | NOVEL SECALONIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1985-08-21 | — | — | EP | claimed |
| CN-116102430-B | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-110283130-B | 1- (2, 5-dimethoxy phenyl) -3-substituted urea colon cancer inhibitor and preparation and application thereof | 温州医科大学 | 2023-12-19 | — | — | CN | disclosed |
| US-11737461-B2 | Citrate perhydrates and uses thereof | BIOREM ENGINEERING SA (CH) | 2023-08-29 | — | — | US | disclosed |
| US-20230210848-A1 | CORONAVIRUS INFECTION THERAPEUTIC AGENT FORMED THROUGH COMBINATION OF PYRAZINE DERIVATIVE AND ANOTHER CORONAVIRUS INFECTION THERAPEUTIC DRUG | FUJIFILM TOYAMA CHEMICAL CO., LTD. (JP) | 2023-07-06 | — | — | US | disclosed |
| CN-116102430-A | Alkylation synthesis method for in-situ catalytic alcohols | 中山大学 | 2023-05-12 | — | — | CN | disclosed |
| US-20230137384-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | URIGEN PHARMACEUTICALS, INC. | 2023-05-04 | — | — | US | disclosed |
| CN-111807971-B | Alkylation synthesis method for in-situ catalysis of alcohols | 中山大学 | 2023-03-24 | — | — | CN | disclosed |
| EP-3998932-A1 | ALKALIZATION OF URINARY BLADDER WALL PRIOR TO TREATMENT WITH INTRAVESICAL HEPARIN AND ALKALINIZED LIDOCAINE TO ENHANCE RELIEF OF BLADDER PAIN SYMPTOMS | Parsons, C. Lowell (US) | 2022-05-25 | — | — | EP | disclosed |
| EP-0114752-A2 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1984-08-01 | — | — | EP | disclosed |
| EP-0114750-A2 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1984-08-01 | — | — | EP | disclosed |
| EP-0112049-A1 | Process for the preparation of beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1984-06-27 | — | — | EP | disclosed |
| EP-0023045-B1 | IMIDAZOLECARBOXYLIC ACID DERIVATIVES OF PENICILLINS AND CEPHALOSPORINS | AJINOMOTO CO., INC. (JP) | 1984-04-11 | — | — | EP | disclosed |
| EP-0080286-A1 | Antibacterial compounds containing beta-lactams, processes for their preparation and their use | BEECHAM GROUP PLC (GB) | 1983-06-01 | — | — | EP | disclosed |
| EP-0068680-A1 | Antibiotics | BEECHAM GROUP PLC (GB) | 1983-01-05 | — | — | EP | disclosed |
| EP-0026644-B1 | ORTHO-TOLYL ESTER OF AN ALPHA-CARBOXY PENICILLIN, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE PENICILLIN | BEECHAM GROUP PLC (GB) | 1982-12-01 | — | — | EP | disclosed |
| EP-0064199-A1 | Novel secalonic acid derivatives and method for preparing thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-11-10 | — | — | EP | disclosed |
| EP-0053539-A1 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | RHONE-POULENC SANTE (FR) | 1982-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210848-A1 | CORONAVIRUS INFECTION THERAPEUTIC AGENT FORMED THROUGH COMBINATION OF PYRAZINE DERIVATIVE AND ANOTHER CORONAVIRUS INFECTION THERAPEUTIC DRUG | ACE2, ACE, SARS1 | POLB 4313/4885MEN1 4715/4885KMT2A 3813/4885 |
| US-20230137384-A1 | ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY | OGFR, ALOX5, PTGS1 | POLB 2761/4885MEN1 4695/4885KMT2A 4584/4885 |
| US-11737461-B2 | Citrate perhydrates and uses thereof | CS, HAGH, HOGA1 | POLB 2280/4885MEN1 2931/4885KMT2A 2310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.