Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557053 | 0.94 | HTR6 (0.41) | HTR6QPCTPARP1CFDF11 | |
| SCHEMBL8559857 | 0.89 | PARP1 (0.36) | HTR6DRD2DRD1QPCTPARP1 | |
| SCHEMBL8560491 | 0.89 | HTR6 (0.43) | HTR6ACHEQPCTPARP1STING1 | |
| SCHEMBL8559319 | 0.87 | TMEM97 (0.36) | DRD2DRD1PARP1 | |
| SCHEMBL8564812 | 0.85 | ESR1 (0.31) | QPCT | |
| SCHEMBL8562406 | 0.82 | HTR6 (0.39) | HTR6ACHEMCHR1QPCTPARP1 | |
| Hydrochloric Acid SCHEMBL8562178 | 0.81 | HTR6 (0.36) | HTR6MCHR1QPCT | |
| Hydrochloric Acid SCHEMBL8564266 | 0.81 | HTR6 (0.37) | HTR6ACHEQPCTPARP1 | |
| Hydrochloric Acid SCHEMBL8559313 | 0.81 | HTR6 (0.41) | HTR6ACHEMCHR1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL8564105 | 0.78 | TBXAS1 (0.38) | HTR6MCHR1QPCTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |