Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560491 | 0.94 | HTR6 (0.43) | HTR6CFDF11PARP1PARP2 | |
| SCHEMBL8562403 | 0.94 | HTR6 (0.40) | HTR6CFDF11PARP1QPCT | |
| SCHEMBL8559857 | 0.86 | PARP1 (0.36) | HTR6PARP1QPCT | |
| SCHEMBL8564812 | 0.84 | ESR1 (0.31) | QPCT | |
| SCHEMBL8559319 | 0.83 | TMEM97 (0.36) | PARP1PTK2 | |
| SCHEMBL8557055 | 0.83 | ITGB3 (0.38) | HTR6PARP1PARP2PARP3ITGB3 | |
| SCHEMBL8560495 | 0.77 | HTR6 (0.43) | HTR6ITGB3ITGA2BQPCT | |
| SCHEMBL8562406 | 0.77 | HTR6 (0.39) | HTR6PARP1ITGB3ITGA2BQPCT | |
| Hydrochloric Acid SCHEMBL8564266 | 0.76 | HTR6 (0.37) | HTR6PARP1ITGB3ITGA2BQPCT | |
| Hydrochloric Acid SCHEMBL8562178 | 0.76 | HTR6 (0.36) | HTR6ITGB3ITGA2BQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |