SCHEMBL8564812

SCHEMBL8564812

CC1(C)NCCc2cc(N3C(=O)NCC3c3ccccc3CCC(=O)O)ccc21

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.31
QPCT Q16769 1/20 0.31
PTGER4 P35408 1/20 0.31
PTGER3 P43115 1/20 0.31
PTGER2 P43116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8562403 0.85 HTR6 (0.40) QPCT
SCHEMBL8564818 0.84 ESR1 (0.39) ESR1QPCT
SCHEMBL8557053 0.84 HTR6 (0.41) QPCT
SCHEMBL8559857 0.83 PARP1 (0.36) QPCTPTGER4PTGER3PTGER2
SCHEMBL8559319 0.80 TMEM97 (0.36)
SCHEMBL8560491 0.80 HTR6 (0.43) QPCT
SCHEMBL8573544 0.72 P2RX3 (0.35) PTGER4PTGER3PTGER2
SCHEMBL8575389 0.71 GAA (0.35) QPCT
SCHEMBL8562965 0.70 ESR1 (0.44) ESR1
Hydrochloric Acid SCHEMBL8564266 0.70 HTR6 (0.37) ESR1QPCT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5827849-A HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT KARL THOMAE GMBH (DE) 1998-10-27 US disclosed