Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.65 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9535454 | 0.88 | KCNH2 (0.51) | KCNH2ABCB1ABCC1ABCG2 | |
| SCHEMBL11266594 | 0.84 | KCNH2 (0.80) | KCNH2CHRNA7TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL1151915 | 0.83 | KCNH2 (0.59) | KCNH2DRD4CHRNA7TSHRMEN1 | |
| SCHEMBL9698375 | 0.82 | KCNH2 (0.66) | KCNH2CHRNA7TSHRMEN1KMT2A | |
| SCHEMBL1101038 | 0.80 | KCNH2 (0.77) | KCNH2CHRNA7TSHR | |
| SCHEMBL7416758 | 0.79 | KCNH2 (0.65) | KCNH2TSHRSMN1; SMN2 | |
| SCHEMBL9690409 | 0.79 | KCNH2 (0.55) | KCNH2DRD4CHRNA7SLC40A1TSHR | |
| SCHEMBL9689809 | 0.79 | KCNH2 (0.72) | KCNH2CHRNA7TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL10749867 | 0.78 | KCNH2 (0.59) | KCNH2CHRNA7TSHR | |
| SCHEMBL9538063 | 0.78 | KCNH2 (1.00) | KCNH2DRD4MEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539421-B1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1998-09-23 | — | — | EP | disclosed |