Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566213 | 1.00 | CA1 (0.49) | CA1CA2CA4CA9CA7 | |
| SCHEMBL8559447 | 0.87 | PTAFR (0.55) | CA1CA2CA4CA9CA7 | |
| SCHEMBL8565136 | 0.83 | CA1 (0.51) | CA1CA2CA4CA9CA7 | |
| SCHEMBL9298870 | 0.82 | PIN1 (0.55) | CA1CA2CA4CA9CA7 | |
| SCHEMBL9595462 | 0.77 | MMP1 (0.53) | CA1CA2CA9CA7MMP2 | |
| SCHEMBL7021143 | 0.76 | NPSR1 (0.59) | CA1CA2CA9ALDH1A1LMNA | |
| SCHEMBL9385459 | 0.75 | CA2 (0.42) | CA1CA2CA4CA9CA7 | |
| SCHEMBL9384827 | 0.75 | CA2 (0.42) | CA1CA2CA4CA9CA7 | |
| SCHEMBL9385461 | 0.75 | CA2 (0.42) | CA1CA2CA4CA9CA7 | |
| SCHEMBL9384830 | 0.75 | CA2 (0.42) | CA1CA2CA4CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543861-B1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BRITISH BIOTECH PHARM (GB) | 1998-10-14 | — | — | EP | disclosed |