Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133560 | 0.90 | MMP1 (0.51) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8563675 | 0.86 | MMP2 (0.47) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8569264 | 0.86 | MMP2 (0.47) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL29827373 | 0.85 | KMT2A (0.58) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL25295317 | 0.84 | L3MBTL1 (0.60) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL25295316 | 0.84 | L3MBTL1 (0.60) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8133802 | 0.81 | ADAMTS4 (0.53) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL29521449 | 0.81 | MMP2 (0.52) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL8583079 | 0.80 | MMP2 (0.45) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL9132706 | 0.80 | MMP1 (0.49) | MMP1MMP2MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015047-A1 | AMINO ACID DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-05 | — | — | WO | disclosed |