Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP7 | P09237 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9384827 | 1.00 | CA2 (0.42) | CA2CA1CA9CA4MMP2 | |
| SCHEMBL7371078 | 0.84 | CA2 (0.58) | CA2CA1CA9CA4MMP2 | |
| SCHEMBL7021143 | 0.78 | NPSR1 (0.59) | CA2CA1CA9ALDH1A1NPSR1 | |
| SCHEMBL9384830 | 0.77 | CA2 (0.42) | CA2CA1CA9CA4MMP2 | |
| SCHEMBL9385461 | 0.77 | CA2 (0.42) | CA2CA1CA9CA4MMP2 | |
| SCHEMBL8565136 | 0.77 | CA1 (0.51) | CA2CA1CA9CA4MMP2 | |
| SCHEMBL8562818 | 0.75 | CA1 (0.49) | CA2CA1CA9CA4MMP2 | |
| SCHEMBL8566213 | 0.75 | CA1 (0.49) | CA2CA1CA9CA4MMP2 | |
| SCHEMBL9595462 | 0.74 | MMP1 (0.53) | CA2CA1CA9MMP2MMP7 | |
| SCHEMBL7447023 | 0.74 | ADAM17 (0.45) | CA2CA1CA9CA4CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605434-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993002080-A1 | IMIDAZO (4,5-C) PYRIDINE DERIVATIVES AS PAF ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |