Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324245 | 0.87 | TSHR (0.42) | ALDH1A1HPGDTSHRHSD17B10DPP4 | |
| SCHEMBL8322260 | 0.86 | DPP4 (0.48) | TSHRDPP4 | |
| SCHEMBL8328855 | 0.86 | DPP4 (0.40) | TSHRDPP4 | |
| SCHEMBL8324234 | 0.80 | DPP4 (0.51) | TSHRHSD17B10DPP4 | |
| SCHEMBL27446746 | 0.80 | TP53 (0.41) | ALDH1A1HPGDTSHRHSD17B10DPP4 | |
| SCHEMBL8565727 | 0.79 | KDM4E (0.33) | ALDH1A1HPGDALOX15TSHRHSD17B10 | |
| SCHEMBL8559490 | 0.78 | CSF1R (0.48) | — | |
| Hydrochloric Acid SCHEMBL8565607 | 0.77 | CSF1R (0.48) | — | |
| SCHEMBL8326372 | 0.77 | TSHR (0.40) | ALDH1A1HPGDTSHRHSD17B10DPP4 | |
| SCHEMBL8561182 | 0.77 | HSD17B10 (0.36) | ALDH1A1HPGDTSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618916-B1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | KNOLL AG (DE) | 1998-09-23 | — | — | EP | disclosed |
| US-5464781-A | TREATING RHEUMATIC DISEASES | THE BOOTS COMPANY PLC (GB) | 1995-11-07 | — | — | US | disclosed |
| EP-0618916-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013097-A1 | ANTI-RHEUMATIC NAPHTHYRIDINE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |