Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832152 | 0.85 | MAPT (0.57) | LMNAMAPTKMT2AALDH1A1TSHR | |
| SCHEMBL10408464 | 0.81 | HSD17B10 (0.56) | LMNAMAPTKMT2AUSP2ALDH1A1 | |
| SCHEMBL8564312 | 0.80 | MAPT (0.56) | LMNAMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL16440154 | 0.78 | ALDH1A1 (0.48) | LMNAMAPTGAAKMT2AUSP2 | |
| SCHEMBL10407236 | 0.78 | ALDH1A1 (0.49) | LMNAMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL9831285 | 0.76 | KDM4E (0.49) | LMNAMAPTGAAKMT2AALDH1A1 | |
| SCHEMBL9830621 | 0.75 | MAOB (0.52) | LMNAMAPTALDH1A1POLBHTT | |
| SCHEMBL7486606 | 0.75 | MAPT (0.56) | LMNAMAPTKMT2AUSP2ALDH1A1 | |
| SCHEMBL12879728 | 0.74 | DRD2 (0.62) | KMT2AALDH1A1TSHRADRA1BKDM4E | |
| SCHEMBL31652018 | 0.73 | HTR3A (0.69) | LMNAMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853622-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997044342-A1 | PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO[3,2-c]QUINOLINE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-11-27 | — | — | WO | disclosed |