Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SI | P14410 | 3/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564148 | 0.90 | LMNA (0.43) | STING1MMP2MMP9HDAC3HDAC4 | |
| SCHEMBL8558984 | 0.87 | MMP13 (0.55) | MGAMGAASIMGAM2MMP2 | |
| SCHEMBL8559057 | 0.87 | MGAM (0.43) | MGAMGAASIMGAM2STING1 | |
| SCHEMBL950269 | 0.77 | MGAM (0.49) | MGAMGAASIMGAM2STING1 | |
| SCHEMBL29678902 | 0.68 | MAPT (0.51) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL7379197 | 0.68 | MMP9 (0.84) | MMP2MMP9HDAC2HDAC8HDAC6 | |
| SCHEMBL7379195 | 0.68 | MMP9 (0.84) | MMP2MMP9HDAC2HDAC8HDAC6 | |
| SCHEMBL949157 | 0.66 | GPR84 (0.49) | MGAMGAASIMGAM2MMP2 | |
| SCHEMBL27517928 | 0.65 | HTR2A (0.49) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL8795676 | 0.65 | GPR84 (0.53) | MGAMGAASIMGAM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804593-A | FOR TREATMENT OF CONNECTIVE TISSUE DEGRADATION, OSTEO-, RHEUMATOID-, AND SEPTIC ARTHRITIS; OSTEOPENIAS, OSTEOPOROSIS, CORNEAL ULCERATION, PERIDONTAL DISEASE, GASTRIC ULCERS. | PHARMACIA & UPJOHN COMPANY (US) | 1998-09-08 | — | — | US | disclosed |