Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.46 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562052 | 0.81 | ALDH1A1 (0.50) | LMNASMN1; SMN2CA9KMT2A | |
| SCHEMBL8563598 | 0.80 | LMNA (0.55) | CYP19A1POLBVCAM1LMNASLC12A2 | |
| SCHEMBL8568512 | 0.79 | CA1 (0.41) | CYP19A1POLBCA12CA9KMT2A | |
| SCHEMBL8567841 | 0.79 | CYP19A1 (0.57) | CYP19A1POLBVCAM1LMNASLC12A2 | |
| SCHEMBL8563864 | 0.79 | NSD2 (0.49) | CYP19A1POLBVCAM1LMNASLC12A2 | |
| SCHEMBL8598890 | 0.78 | TSHR (0.34) | CYP19A1SMN1; SMN2CA12CA9KMT2A | |
| SCHEMBL8569474 | 0.77 | HTT (0.49) | POLBLMNASMN1; SMN2KMT2A | |
| SCHEMBL8601240 | 0.76 | RECQL (0.40) | CYP19A1POLBLMNASMN1; SMN2CA12 | |
| SCHEMBL8566052 | 0.74 | NSD2 (0.49) | CYP19A1POLBVCAM1LMNASLC12A2 | |
| SCHEMBL8561895 | 0.74 | HTT (0.52) | CYP19A1POLBVCAM1LMNASLC12A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |