Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568520 | 0.77 | BACE1 (0.56) | HTTPOLBSMN1; SMN2MAPTMEN1 | |
| SCHEMBL8563126 | 0.77 | CYP19A1 (0.50) | POLBSMN1; SMN2KMT2ALMNA | |
| SCHEMBL8566566 | 0.77 | CYP1A2 (0.52) | HTTPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8562887 | 0.77 | BACE1 (0.52) | HTTPOLBSMN1; SMN2MAPTMEN1 | |
| SCHEMBL8568534 | 0.76 | CYP19A1 (0.40) | HTTPOLBSMN1; SMN2MAPTLMNA | |
| SCHEMBL12205175 | 0.76 | HTR6 (0.66) | HTTMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL8560894 | 0.76 | HTR6 (0.55) | HTTPOLBSMN1; SMN2MAPTMEN1 | |
| SCHEMBL8603087 | 0.75 | HCAR3 (0.42) | HTTSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL4619552 | 0.74 | KMT2A (0.53) | MAPTMEN1KMT2A | |
| SCHEMBL8561788 | 0.73 | ALDH1A1 (0.47) | POLBSMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |