Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424340 | 0.84 | OPRL1 (0.51) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL8520123 | 0.83 | MAPT (0.49) | — | |
| SCHEMBL8520559 | 0.80 | DRD2 (0.38) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL8563172 | 0.79 | HTR1D (0.53) | SIGMAR1 | |
| SCHEMBL8425551 | 0.77 | GRIN2B (0.50) | OPRL1OPRM1OPRD1OPRK1CACNA1G | |
| SCHEMBL3208971 | 0.73 | OPRM1 (0.49) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL6110923 | 0.72 | OPRL1 (0.79) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL8422440 | 0.72 | SLC6A2 (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL8424657 | 0.72 | OPRL1 (0.49) | OPRL1OPRM1OPRD1OPRK1DRD2 | |
| Bromide SCHEMBL10842432 | 0.72 | MAOA (0.44) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |