Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563162 | 0.89 | LMNA (0.32) | — | |
| SCHEMBL6371677 | 0.79 | DGAT1 (0.34) | ALDH1A1 | |
| SCHEMBL29169989 | 0.77 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL21693639 | 0.74 | DGAT1 (0.45) | — | |
| SCHEMBL5697048 | 0.74 | LMNA (0.35) | ALDH1A1TSHR | |
| SCHEMBL8563422 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL29170737 | 0.72 | PTPN1 (0.39) | TSHR | |
| SCHEMBL2073077 | 0.72 | ALDH1A1 (0.37) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7591963 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10TDP1 | |
| Phosphoric Acid SCHEMBL10414686 | 0.67 | ALDH1A1 (0.71) | ALDH1A1TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526642-B1 | TRITERPENE DERIVATIVE | SHIONOGI & CO (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5248807-A | Endothelin antagonists, treatment of cardiovascular disorders | SHIONOGI & CO., LTD. (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0526642-A1 | TRITERPENE DERIVATIVE | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-10 | — | — | EP | disclosed |