Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563175 | 0.89 | ALDH1A1 (0.38) | — | |
| SCHEMBL6371677 | 0.85 | DGAT1 (0.34) | LMNAFDPS | |
| SCHEMBL21693639 | 0.79 | DGAT1 (0.45) | LMNAFDPS | |
| SCHEMBL5697048 | 0.79 | LMNA (0.35) | LMNAFDPS | |
| SCHEMBL2073077 | 0.78 | ALDH1A1 (0.37) | LMNA | |
| SCHEMBL29170737 | 0.78 | PTPN1 (0.39) | — | |
| SCHEMBL29169989 | 0.77 | LMNA (0.33) | LMNAFDPS | |
| SCHEMBL8563414 | 0.69 | LMNA (0.41) | LMNAFDPS | |
| Phosphoric Acid Monomethyl Ester SCHEMBL28225629 | 0.63 | L3MBTL1 (0.30) | — | |
| SCHEMBL992 | 0.62 | DGAT1 (0.41) | LMNAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526642-B1 | TRITERPENE DERIVATIVE | SHIONOGI & CO (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5248807-A | Endothelin antagonists, treatment of cardiovascular disorders | SHIONOGI & CO., LTD. (JP) | 1993-09-28 | — | — | US | disclosed |
| EP-0526642-A1 | TRITERPENE DERIVATIVE | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-10 | — | — | EP | disclosed |