Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445321 | 0.89 | OPRL1 (0.52) | OPRL1CHRM3CHRM2DRD2DRD4 | |
| SCHEMBL6168606 | 0.89 | OPRL1 (0.52) | OPRL1CHRM3CHRM2DRD2DRD4 | |
| SCHEMBL8569508 | 0.85 | MEN1 (0.53) | OPRL1CHRM3CHRM2DRD2DRD4 | |
| SCHEMBL8565096 | 0.84 | CCR5 (0.48) | OPRL1CHRM3CHRM2ACHECCR5 | |
| SCHEMBL6168165 | 0.83 | CHRM3 (0.49) | OPRL1CHRM3CHRM2DRD2DRD4 | |
| SCHEMBL8570369 | 0.83 | CHRM3 (0.50) | OPRL1CHRM3CHRM2DRD2DRD4 | |
| SCHEMBL8568370 | 0.82 | TRPV6 (0.48) | OPRL1CHRM3CHRM2PARP2DRD2 | |
| SCHEMBL6167277 | 0.82 | CHRM3 (0.53) | OPRL1CHRM3CHRM2DRD2DRD4 | |
| SCHEMBL8570499 | 0.82 | CHRM3 (0.55) | CHRM3CHRM2DRD2DRD4DRD3 | |
| SCHEMBL8564439 | 0.82 | CHRM2 (0.55) | OPRL1CHRM3CHRM2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |