Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559172 | 0.93 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4ETSHRGAA | |
| SCHEMBL8567545 | 0.89 | MAPT (0.42) | MAPTALDH1A1KDM4ETSHRGAA | |
| SCHEMBL8566120 | 0.83 | MAPT (0.42) | MAPTALDH1A1KDM4ETSHRGAA | |
| SCHEMBL8560752 | 0.81 | LPAR1 (0.47) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL8561511 | 0.78 | KDM4E (0.45) | MAPTALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30622065 | 0.73 | HSD17B1 (0.75) | HSD17B1HSD17B2MAPTALDH1A1KDM4E | |
| SCHEMBL2191052 | 0.73 | HSD17B1 (0.75) | HSD17B1HSD17B2MAPTALDH1A1KDM4E | |
| SCHEMBL4852258 | 0.72 | KDM4E (0.58) | HSD17B1HSD17B2ALDH1A1KDM4EMEN1 | |
| SCHEMBL8564973 | 0.72 | LPAR1 (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6952681 | 0.69 | KDM4E (0.56) | HSD17B1HSD17B2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770438-A | CHEMICAL INTERMEDIATES FOR ANTICHOLESTEROL COMPOUNDS, CYCLIZATION TO FORM BENZOXAZEPINE OR BENZOTHIAZEPINE COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-06-23 | — | — | US | disclosed |
| EP-0710725-A1 | Production of optically active compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |