Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MGMT | P16455 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567950 | 0.81 | CYP3A4 (0.47) | MAPTMGMTCYP3A4HPGDLMNA | |
| SCHEMBL3953291 | 0.80 | KDM4E (0.52) | MAPTMGMTCYP3A4HPGDLMNA | |
| SCHEMBL8570788 | 0.79 | BACE1 (0.42) | BACE1MAPTHPGDLMNAIGF1R | |
| SCHEMBL8562792 | 0.79 | MGMT (0.40) | BACE1MAPTMGMTCYP3A4HPGD | |
| SCHEMBL8568375 | 0.78 | PDE10A (0.46) | MAPTMGMTCYP3A4LMNAMEN1 | |
| SCHEMBL8562456 | 0.77 | CYP3A4 (0.43) | MAPTMGMTCYP3A4HPGDLMNA | |
| SCHEMBL12518927 | 0.77 | MAOA (0.48) | MAPTMGMTCYP3A4HPGDLMNA | |
| SCHEMBL8567514 | 0.77 | S100A4 (0.54) | MAPTMGMTCYP3A4HPGDLMNA | |
| SCHEMBL8561217 | 0.77 | ABCC8 (0.43) | BACE1MAPTCYP3A4HPGDLMNA | |
| SCHEMBL8564301 | 0.76 | KDM4E (0.47) | MAPTMGMTCYP3A4HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |