Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563396 | 0.82 | CES2 (0.39) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8564029 | 0.79 | KDM4E (0.55) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8564284 | 0.79 | POLB (0.63) | KMT2AMEN1ALDH1A1HTTPOLB | |
| SCHEMBL8561998 | 0.79 | NSD2 (0.60) | KMT2AMEN1MAPTHTTLMNA | |
| SCHEMBL8559950 | 0.78 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8566020 | 0.77 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8562600 | 0.76 | LMNA (0.47) | KMT2AALDH1A1MAPTHTTPOLB | |
| SCHEMBL7371695 | 0.75 | NAPRT (0.61) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL8560948 | 0.74 | MAPT (0.51) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL8567678 | 0.74 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |