Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564375 | 0.82 | KMT2A (0.46) | CES2CES1KDM4EKMT2AMEN1 | |
| SCHEMBL8562600 | 0.81 | LMNA (0.47) | CES2CES1KDM4EKMT2AALDH1A1 | |
| SCHEMBL8560654 | 0.81 | RAB9A (0.52) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL8561698 | 0.81 | NSD2 (0.50) | KMT2AMEN1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL8560442 | 0.79 | KDM4E (0.45) | KDM4EASPHKDM8KMT2AMEN1 | |
| SCHEMBL8559950 | 0.77 | ALDH1A1 (0.39) | CES2CES1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8566712 | 0.77 | CYP19A1 (0.43) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8567497 | 0.76 | ALDH1A1 (0.42) | KDM4EASPHKDM8KMT2AMEN1 | |
| SCHEMBL8563829 | 0.75 | MAPK1 (0.37) | KDM4EASPHKDM8KMT2AALDH1A1 | |
| SCHEMBL8564862 | 0.75 | KDM4E (0.37) | CES2CES1KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |