Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MGMT | P16455 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565798 | 0.81 | RAB9A (0.55) | MAPTMGMTALDH1A1LMNAPOLB | |
| SCHEMBL8565140 | 0.81 | HTT (0.55) | HTTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL8566551 | 0.78 | ALDH1A1 (0.46) | HTTMAPTALDH1A1LMNAPOLB | |
| SCHEMBL8561530 | 0.76 | HTT (0.52) | CES2CES1HTTMAPTALDH1A1 | |
| SCHEMBL8562600 | 0.76 | LMNA (0.47) | CES2CES1HTTMAPTMGMT | |
| SCHEMBL8568617 | 0.75 | MAPK1 (0.38) | CES2CES1HTTMAPTALDH1A1 | |
| SCHEMBL30967226 | 0.75 | MAPK1 (0.44) | CES2CES1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8563757 | 0.75 | ALDH1A1 (0.40) | HTTMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8564450 | 0.74 | MAPT (0.41) | HTTMAPTMGMTALDH1A1SMN1; SMN2 | |
| SCHEMBL8569903 | 0.73 | MAPK1 (0.34) | HTTMAPTALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |