Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567165 | 0.81 | PIN1 (0.40) | HPGDCYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL8566566 | 0.78 | CYP1A2 (0.52) | HPGDCYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL8560325 | 0.78 | RAB9A (0.51) | HTTPOLBKMT2A | |
| SCHEMBL8597304 | 0.78 | ALOX15 (0.43) | HPGDCYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL19246188 | 0.77 | KMT2A (0.75) | HPGDCYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL30236290 | 0.77 | KMT2A (0.75) | HPGDCYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL8560894 | 0.77 | HTR6 (0.55) | CYP1A2CYP3A4CYP2C19HTTPOLB | |
| SCHEMBL8567201 | 0.77 | HTT (0.73) | HPGDCYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL9646491 | 0.77 | POLB (0.64) | HPGDCYP1A2CYP3A4CYP2C19HTT | |
| SCHEMBL21296309 | 0.76 | HPGD (0.63) | HPGDCYP1A2CYP3A4CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |