Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NSD2 | O96028 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559950 | 0.81 | ALDH1A1 (0.39) | CYP1A2CYP2C19CYP3A4HTTGAA | |
| SCHEMBL8561998 | 0.80 | NSD2 (0.60) | CYP1A2CYP2C19HPGDCYP3A4NSD2 | |
| SCHEMBL8561698 | 0.79 | NSD2 (0.50) | CYP1A2CYP2C19HPGDCYP3A4NSD2 | |
| SCHEMBL8567302 | 0.78 | RAB9A (0.51) | CYP3A4HTTKMT2APOLBLMNA | |
| SCHEMBL8565663 | 0.78 | HPGD (0.58) | CYP1A2CYP2C19HPGDCYP3A4NSD2 | |
| SCHEMBL8599306 | 0.78 | ATG4B (0.43) | CYP1A2CYP2C19HPGDCYP3A4HTT | |
| SCHEMBL8569474 | 0.77 | HTT (0.49) | CYP1A2CYP2C19HPGDCYP3A4HTT | |
| SCHEMBL8597941 | 0.76 | HTR2A (0.43) | HPGDHTTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL6940724 | 0.76 | MEN1 (0.61) | CYP1A2CYP2C19HPGDCYP3A4NSD2 | |
| SCHEMBL8563141 | 0.75 | ALDH1A1 (0.44) | CYP1A2CYP2C19HPGDCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |