Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565695 | 1.00 | KMT2A (0.42) | KMT2AALDH1A1SMN1; SMN2KDM4EGLA | |
| SCHEMBL8559988 | 0.85 | NFE2L2 (0.47) | KMT2AALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL27504823 | 0.81 | KMT2A (0.40) | KMT2AALDH1A1SMN1; SMN2KDM4EGLA | |
| SCHEMBL8601047 | 0.78 | POLB (0.39) | KMT2AALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL8601050 | 0.78 | POLB (0.39) | KMT2AALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL8568103 | 0.76 | RAB9A (0.46) | KMT2AALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL8568102 | 0.76 | RAB9A (0.46) | KMT2AALDH1A1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL3298254 | 0.76 | KMT2A (0.54) | KMT2AALDH1A1SMN1; SMN2POLBMEN1 | |
| SCHEMBL8570733 | 0.75 | ALDH1A1 (0.46) | KMT2AALDH1A1SMN1; SMN2KDM4EGLA | |
| SCHEMBL3956436 | 0.74 | NCF1 (0.51) | KMT2AALDH1A1SMN1; SMN2KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |