Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562778 | 0.83 | RIPK1 (0.47) | ALDH1A1KMT2ASMN1; SMN2POLBKDM4E | |
| SCHEMBL8601044 | 0.80 | MAPT (0.40) | ALDH1A1KMT2ASMN1; SMN2POLBKDM4E | |
| SCHEMBL3298254 | 0.78 | KMT2A (0.54) | ALDH1A1TSHRKMT2ASMN1; SMN2POLB | |
| SCHEMBL8563057 | 0.78 | POLB (0.46) | ALDH1A1KMT2ASMN1; SMN2POLBKDM4E | |
| SCHEMBL8599261 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL3956436 | 0.77 | NCF1 (0.51) | ALDH1A1TSHRKMT2ASMN1; SMN2POLB | |
| SCHEMBL3272390 | 0.77 | MAPT (0.58) | ALDH1A1TSHRKMT2ASMN1; SMN2POLB | |
| SCHEMBL8566513 | 0.77 | CASP6 (0.44) | ALDH1A1KMT2ASMN1; SMN2POLBKDM4E | |
| SCHEMBL8569955 | 0.77 | KMT2A (0.42) | ALDH1A1KMT2ASMN1; SMN2POLBKDM4E | |
| SCHEMBL8565695 | 0.75 | KMT2A (0.42) | ALDH1A1KMT2ASMN1; SMN2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |