Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561101 | 0.78 | POLB (0.53) | MEN1KMT2AS100A4ALDH1A1POLB | |
| SCHEMBL202480 | 0.77 | MEN1 (0.45) | MEN1KMT2AS100A4ALDH1A1POLB | |
| SCHEMBL9602589 | 0.77 | S100A4 (0.53) | MEN1KMT2AS100A4ALDH1A1POLB | |
| SCHEMBL8568380 | 0.77 | MEN1 (0.45) | MEN1KMT2AS100A4ALDH1A1POLB | |
| SCHEMBL31581131 | 0.77 | MEN1 (0.45) | MEN1KMT2AS100A4ALDH1A1POLB | |
| SCHEMBL12157826 | 0.73 | MAOA (0.45) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL15337220 | 0.73 | KDM4E (0.45) | MEN1KMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL20291524 | 0.71 | CYP3A4 (0.61) | MEN1KMT2AS100A4ALDH1A1POLB | |
| SCHEMBL10904937 | 0.70 | NPY1R (0.55) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9770640 | 0.67 | CTSB (0.54) | MEN1KMT2AALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089757-C | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 2002-08-28 | — | — | CN | disclosed |
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| CN-1138033-A | Process for produducing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |