Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912954 | 0.69 | GABRA5 (0.44) | POLBSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL6299572 | 0.66 | CYP19A1 (0.52) | POLBALDH1A1TSHRGAANPC1 | |
| SCHEMBL19521779 | 0.65 | MAOA (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30532162 | 0.64 | GRIN1 (0.49) | POLBSMN1; SMN2MAPTALDH1A1NPSR1 | |
| SCHEMBL29236649 | 0.62 | GLA (0.61) | POLBSMN1; SMN2MAPTALDH1A1NPSR1 | |
| SCHEMBL711360 | 0.62 | RAB9A (0.75) | POLBSMN1; SMN2ALDH1A1KDM4ETSHR | |
| SCHEMBL2216212 | 0.62 | ALDH1A1 (1.00) | POLBSMN1; SMN2ALDH1A1TSHRCTNNB1 | |
| SCHEMBL15980187 | 0.62 | LMNA (0.72) | POLBMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL652034 | 0.61 | CTNNB1 (1.00) | POLBALDH1A1TSHRCTNNB1NPC1 | |
| Hydrochloric Acid SCHEMBL27854977 | 0.61 | CTNNB1 (0.60) | POLBSMN1; SMN2ALDH1A1CTNNB1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571253-B1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5639756-A | ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-06-17 | — | — | US | disclosed |
| EP-0571253-A1 | Benzimidazole derivatives with antidiabetic and antiplatelet aggregation activity | ADIR ET COMPAGNIE (FR) | 1993-11-24 | — | — | EP | disclosed |