SCHEMBL8567693

SCHEMBL8567693

[CH2]C(Cc1ccccc1)c1ncco1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
CES1 P23141 2/20 0.36
FAAH O00519 1/20 0.36
NCEH1 Q6PIU2 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
EPHX1 P07099 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CNR1 P21554 1/20 0.34
TSHR P16473 1/20 0.34
KDM4E B2RXH2 2/20 0.34
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPK10 P53779 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CTSA P10619 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668396 0.81 CES1 (0.40) MIFSLC6A2SLC6A4SLC6A3CES1
SCHEMBL27199621 0.79 ALDH1A1 (0.44) SLC6A2SLC6A4SLC6A3L3MBTL1EPHX1
SCHEMBL22885996 0.74 LAP3 (0.40) SLC6A2SLC6A4SLC6A3CES1FAAH
Hydrochloric Acid SCHEMBL6349633 0.73 LAP3 (0.39) SLC6A2SLC6A4SLC6A3CES1FAAH
SCHEMBL28171270 0.71
SCHEMBL25922311 0.70 LTA4H (0.55) SLC6A2SLC6A3CES1L3MBTL1MAPT
SCHEMBL5641212 0.70 MIF (0.40) MIFCES1FAAHNCEH1CTSA
SCHEMBL13129849 0.70 KMT2A (0.41) CES1FAAHNCEH1ALDH1A1TSHR
SCHEMBL13129847 0.70 FAAH (0.44) CES1FAAHNCEH1
SCHEMBL8560552 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821675-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-02-04 EP disclosed
WO-1996033176-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-10-24 WO disclosed