Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13129847 | 0.85 | FAAH (0.44) | CES1FAAHNCEH1 | |
| SCHEMBL6207882 | 0.83 | FAAH (0.49) | CES1FAAHNCEH1 | |
| SCHEMBL22885996 | 0.82 | LAP3 (0.40) | CES1FAAHNCEH1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6349633 | 0.81 | LAP3 (0.39) | CES1FAAHNCEH1SLC6A2SLC6A4 | |
| SCHEMBL8567693 | 0.81 | MIF (0.37) | CES1FAAHNCEH1MIFSLC6A2 | |
| SCHEMBL27199621 | 0.81 | ALDH1A1 (0.44) | SLC6A2SLC6A4SLC6A3CYP1A2EPHX1 | |
| SCHEMBL5641212 | 0.75 | MIF (0.40) | CES1FAAHNCEH1MIFCYP1A2 | |
| SCHEMBL6476667 | 0.74 | GRIN2D (0.40) | CTSA | |
| SCHEMBL474256 | 0.74 | SMN1; SMN2 (0.48) | CTSAALDH1A1 | |
| SCHEMBL5954984 | 0.73 | METAP2 (0.41) | CES1FAAHNCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024939-A2 | LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR, AND METHODS OF USE THEREOF | GEORGETOWN UNIVERSITY (US) | 2004-03-25 | — | — | WO | disclosed |