Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566848 | 0.87 | TACR1 (0.53) | TACR1ALDH1A1POLQCD274PDCD1 | |
| SCHEMBL8570068 | 0.84 | TACR1 (0.60) | TACR1ALDH1A1POLQCD274PDCD1 | |
| SCHEMBL8565708 | 0.80 | TACR1 (0.60) | TACR1POLQCD274PDCD1MAPT | |
| SCHEMBL8572409 | 0.77 | TACR1 (0.69) | TACR1POLQ | |
| SCHEMBL8567776 | 0.75 | KMT2A (0.43) | TACR1ALDH1A1POLQCD274PDCD1 | |
| SCHEMBL8720338 | 0.73 | TACR1 (0.57) | TACR1ALDH1A1KMT2ALTB4R2L3MBTL1 | |
| SCHEMBL31443047 | 0.73 | TRPM8 (0.46) | ALDH1A1POLQKMT2ALMNATRPM8 | |
| SCHEMBL8574194 | 0.72 | TACR1 (0.43) | TACR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL868679 | 0.71 | PTGS2 (0.54) | KMT2ATDP1GRIN2BMAPTMEN1 | |
| SCHEMBL6871097 | 0.70 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |