Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PDE6D | O43924 | 5/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168606 | 0.85 | OPRL1 (0.52) | DRD2OPRL1DRD4DRD3CHRM2 | |
| SCHEMBL29445321 | 0.85 | OPRL1 (0.52) | DRD2OPRL1DRD4DRD3CHRM2 | |
| SCHEMBL8564971 | 0.85 | TACR1 (0.43) | DRD2OPRL1TACR1DRD4DRD3 | |
| SCHEMBL6168102 | 0.84 | CHRM3 (0.42) | DRD2OPRL1TACR1DRD4DRD3 | |
| SCHEMBL8567952 | 0.83 | SLC18A3 (0.49) | SIGMAR1OPRL1TACR1PDE6D | |
| SCHEMBL8565908 | 0.83 | TACR1 (0.41) | OPRL1TACR1CHRM2CHRM3 | |
| SCHEMBL8565287 | 0.82 | CHRM3 (0.53) | DRD2SIGMAR1DRD4CHRM1CHRM3 | |
| SCHEMBL8571012 | 0.82 | CHRM2 (0.49) | DRD2SIGMAR1OPRL1DRD4CHRM2 | |
| SCHEMBL8571710 | 0.82 | PRCP (0.42) | DRD2SIGMAR1OPRL1TACR1PDE6D | |
| SCHEMBL6168284 | 0.82 | TACR1 (0.41) | OPRL1TACR1PDE6DCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626373-B1 | Quinazolinone derivatives | SUMITOMO PHARMA (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5556860-A | ANTIISCHEMIC AGENTS, BRAIN DISORDERS AND BLOOD METAL CONCENTRATIONS AND KIDNEY DISEASE | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0626373-A1 | Quinazolinone derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |